Toxicity study of the traditional and nano-form of propamocarb- -HCl on cucumber and their toxicity on HPG2 Line

Document Type : Original Article

Authors

1 Central Agricultural Pesticides Laboratory (CAPL), Agricultural Research Centre (ARC), 12618-Dokki, Giza, Egypt.

2 Nanotechnology and Advanced Materials Central Lab., Regional Center for Food and Feed, Agricultural Research Center, Giza, Egypt

3 Abd El- Hameed El Hawary Street, No 7- 4th floor

4 Vegetable crop Department, Faculty of Agriculture, Cairo University, Giza 12613, Egypt

Abstract

Phytotoxic means harmful or fatal to plants. Phytotoxicity is the degree to which chemicals or other compounds are toxic to the plants. The phytotoxic effects of some pesticides may be presented in negative effects on the growth rate of the treated plant. Phytotoxic effects of propamocarb-HCl pesticide and its Nano form on cucumber plant and their adverse impact on tissue culture of HpG2 line were studied. Nano form was loaded on chitosan nanoparticles (NPs). Significant increase in plant morphological parameters was noticed after the last periods of transplanting. Also, it exhibited significant increases in fruits yield greater than the traditional form. The quality recognized the same pattern. All treatments doses, ½ doses, and double doses showed an increase in leave pigments in the case of nano-form treatments greater than the traditional form. Biosafety profile on HPG2 cell lines showed a slight difference with 1.22 folds between the traditional and nano-form. While, lactate dehydrogenase (LDL) and malondialdehyde (MDA) showed a significant increase, compared to their control. Such this finding provides the advantage of nano-formation on vegetable crops, but it must be coupled with further toxicological studied.

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